24 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
and progressive fibrosis ... skin thickening Signs ... : ILD (interstitial ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Tram Track Sign on Chest CT
 • Parallel, non-tapering airways, extending to the lung periphery.
 •
Tram Track Sign ... bronchiectasis, CF, ILD ... #CT #Lung #Pulmonary ... #diagnosis #radiology ... #clinical
Air Bronchogram Sign on Chest CT
 • Patent airways surrounded by opacified lung
 • DDx: pna,
Air Bronchogram Sign ... edema, severe ILD ... #CT #Lung #Pulmonary ... #diagnosis #radiology ... #clinical
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
interstitial lung disease/pulmonary ... fibrosis (mechanism ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms ... #diagnosis #ExtraArticular
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... : 33% • Treatment ... , and CXR with pulmonary ... : No • Treatment ... #diagnosis #comparison
Galaxy Sign on Chest CT
 • Coalescent granuloma with a central dense mass and tiny peripheral
Galaxy Sign on Chest ... progressive massive fibrosis ... #CT #Lung #Pulmonary ... #diagnosis #radiology ... #clinical
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
or the anterior chest ... (in a V-sign), ... auricular papules Clinical ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Bronchiectasis - Summary

What?
• Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
Causes: • Cystic fibrosis ... evidence of cystic fibrosis ... Nasal polyps and signs ... parenchyma Diagnosis ... mycobacteria Treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... cytokines (TNFa,lL1, IL6 ... accumulation of clinical ... Assessment • Clinical ... #summary #rheumatology
Chronic Thromboembolic Pulmonary Hypertension (CTEPH) and Pulmonary Thromboendarterectomy
Chronic Thromboembolic Pulmonary Hypertension
Definition: mean pulmonary-artery pressure > 25mmHg
embolism Pathophysiology ... Plexiform-lesion formation Clinical ... regurgitation) Diagnosis ... not specific • Chest ... Bypass Other Treatment