127 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
and progressive fibrosis ... calcinosis • Pulmonary ... : ILD (interstitial ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Interstitial Lung Diseases (ILD)
Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): 
 • Hypersensitivity pneumonitis, Farmer's lung, Bird
Tissue Disease: • Systemic ... • Idiopathic pulmonary ... fibrosis (IPF), ... #diagnosis #differential ... #pulmonary #causes
Systemic Sclerosis Associated Autoantibodies
Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis
Anti-centromere: Limited skin disease (~93-95%), Pulmonary
Systemic Sclerosis ... skin disease, Pulmonary ... fibrosis Anti-centromere ... Autoantibodies #diagnosis ... #rheumatology
Diagnostic algorithm for idiopathic pulmonary fibrosis, in part adapted from the ATS/ERS consensus statement. HRCT =
Diagnostic algorithm ... fibrosis, in part ... computerised tomography; ILD ... UIP #Algorithm #Diagnosis ... #Fibrosis
ILD of Known Cause - Differential Diagnosis
Exposure:
 • Occupational: Asbestosis, Silicosis, Hypersensitivity, Pneumonitis
 • Treatment Related:
ILD of Known Cause ... - Differential Diagnosis ... Pneumonitis • Treatment ... Chemotherapeutic Systemic ... lung #disease #pulmonary
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
SSc: systemic sclerosis ... ConnectiveTissueDiseases #ILD ... LungDisease #CTILD #Diagnosis ... Comparison #Table #Pulmonary ... #Rheumatology #
Management of interstitial lung disease (ILD)-associated with systemic sclerosis (SSc)

Therapeutic indication: absolute decline in FVC >10%
lung disease (ILD ... associated with systemic ... Symptomatic treatment ... #lungdisease #ILD ... systemicsclerosis #SSc #pulmonary
Systemic Sclerosis (Scleroderma)
Limited - CREST:
 • Calcinosis
 • Raynaud phenomenon
 • Esophageal dysmotility
 • Sclerodactyly
 •
Systemic Sclerosis ... Diffuse - Involves Fibrosis ... @AnnKumfer #Systemic ... #Scleroderma #diagnosis ... signs #symptoms #rheumatology
Seronegative Inflammatory Arthritis - Differential Diagnosis
 • Seronegative Rheumatoid Arthritis 
 • Infectious Arthritis: Viral, Bacterial,
- Differential Diagnosis ... Vasculitis, Systemic ... Psoriatic Arthritis, IBD-Associated ... #Differential #Diagnosis ... #rheumatology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
weakness, less systemic ... Classic triad of ILD ... /full triad at diagnosis ... after 2 years of treatment ... #rheumatology