11 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin ... Cold Agglutinins ... nose, ears, or fingers ... anemiaCold ... #hemolytic #anemia
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Smear Analysis ... #Smear #Analysis ... #hematology #microscopy ... interpretation #clinical
Dacrocytes (tear drop cells) 
Other poikilocytes resemble a pear or teardrop. The narrow, tapered end
may be
each of the above photos ... thalassemia, and some hemolytic ... #Clinical #Path ... #BloodSmear #Blood ... #Smear #Dacrocytes
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... DIC is a clinical ... arrow) Peripheral smear ... #anemia #Hematology ... #Pathology #Smear
Spur-Cell Anemia- A 31-year-old man with a history of cirrhosis, recurrent hepatic encephalopathy, and anemia presented
- A 31-year-old ... smear showed numerous ... , a form of hemolytic ... #NEJM #clinical ... #smear
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Autoimmune: Warm AIHA, Cold ... Defects: Sickle cell anemia ... - Peripheral Blood ... Smear ↑ abnormal
Codocytes (Target cells) - Two target cells are seen in the left photo and one in
associated with hemolytic ... anemias, especially ... #Clinical #Path ... #BloodSmear #Blood ... #Smear #Codocytes
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
fragmented red blood ... In the right photo ... anemia in which ... #Clinical #Path ... #Smear #Schistocytes
Spherocytes - The arrow points to one of many spherocytes in this photo. The cells have
spherocytes in this photo ... spherocytosis and hemolytic ... anemias. ... #Clinical #Path ... #BloodSmear #Blood
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
A 37-year-old woman ... promyelocytes, anemia ... bilobed nuclei, fine ... #Clinical #Path ... #BloodSmear #Blood