14 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Diagnosis: • hemolytic ... • Compensated hemolysis ... intravascular hemolysis ... #disease #hemolytic ... #anemia #hematology
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Smear Analysis ... Microangiopathic hemolytic ... Microspherocytes: Autoimmune hemolytic ... interpretation #clinical
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... microangiopathic hemolytic ... Microangiopathic hemolytic ... microangiopathic #hemolytic ... #anemia #Hematology
Dacrocytes (tear drop cells) 
Other poikilocytes resemble a pear or teardrop. The narrow, tapered end
may be
each of the above photos ... thalassemia, and some hemolytic ... #Clinical #Path ... #BloodSmear #Blood ... #Smear #Dacrocytes
Spur-Cell Anemia- A 31-year-old man with a history of cirrhosis, recurrent hepatic encephalopathy, and anemia presented
smear showed numerous ... , a form of hemolytic ... inflexible and prone to hemolysis ... #NEJM #clinical ... #smear
Codocytes (Target cells) - Two target cells are seen in the left photo and one in
associated with hemolytic ... anemias, especially ... #Clinical #Path ... #BloodSmear #Blood ... #Smear #Codocytes
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
In the right photo ... to be seen in hemolytic ... microangiopathic hemolytic ... intravascular coagulation, hemolytic ... #Smear #Schistocytes
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
hemorrhage and hemolysis ... intravascular hemolysis ... of Peripheral blood ... out an immune hemolytic ... the severity of hemolysis
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Defects: Sickle cell anemia ... - Peripheral Blood ... Smear ↑ abnormal ... Urobilinogen #Hemolysis
Spherocytes - The arrow points to one of many spherocytes in this photo. The cells have
spherocytes in this photo ... spherocytosis and hemolytic ... anemias. ... #Clinical #Path ... #BloodSmear #Blood