9 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... predispose to other orthopedic ... common sites: hip, shoulder ... • Differentiate ... #hematology
Etiologies of Folate Deficiency
 • Decreased dietary intake - uncommon in this era
 • Increased requirements
folate that can cause ... Alcoholics have an inability ... mobilize folate stores ... deficiency #FolicAcid #differential ... #diagnosis #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Arterial Thrombosis - Differential ... • Nephrotic Syndrome ... antibodies (APLS should ... pathophysiology #hematology ... #differential #
Pustular Skin Lesions - Differential Diagnosis Framework

What are pustules?
• Pustules < 5-10 mm + pus
• Material
Skin Lesions - Differential ... Burrows between fingers ... Mpox • Starts ... SAPHO syndrome ( ... #Diagnosis #Dermatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... Pinpoint-sized red spots ... skin that are caused ... blood count with differential ... #diagnosis #hematology
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Allopecia - Differential ... , Loose anagen syndrome ... texture at bald spots ... loss #alopecia #Differential ... #Diagnosis #dermatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
of Hemostasis - Differential ... von Willebrand syndrome ... of factor VII should ... discern these causes ... #Diagnosis #Hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Vasculitis Differential ... proximal muscles of shoulder ... tract, and often causes ... #Diagnosis #Rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
gap (>4 g/dL) should ... changes (POEMS syndrome ... gastric tumors • Hematology ... Gap #ProteinGap #differential ... #diagnosis #hematology