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differential hematology hemolytic symptoms agglutinin algorithm anorexianervosa causes classification complications disease dyspnea erythematosus lupus monoclonal oncology paraproteinemias pathophysiology psychiatry pulmonary
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... nose, ears, or fingers ... • Symptoms of anemia ... anemia • Cold ... #hematology #diagnosis
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
- Differential Diagnosis ... - Asthma - COPD ... Pulmonary HTN - Vasculitis ... Transverse myelitis • Hematology ... : - Anemia •
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
, Vasculitis, Purpura ... ) Blood (75%): Anemia ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... Agglutination - Cold ... cardiac valve, vasculitis ... Algorithm #workup #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... mucositis - Rash ... episcleritis as well as inner ... purpura: strong sign ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... Differential Diagnosis ... purpura: Strong sign ... , mucositis • Rash ... #Rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Autoimmunity: • -MM/WM: Vasculitis ... (-) hemolytic anemia ... due to cold IgG ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Anorexia Nervosa: Complications CARDIAC ABNORMALITIES - Functional: Low BP, Sinus bradycardia, prolonged QT interval - Structural: Reduced
lymphocytosis, mild anemia ... risk of fracture DERMATOLOGIC ... Hypothermia and Cold ... pathophysiology #diagnosis ... #signs #symptoms
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