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differential pathophysiology rheumatology vasculitis autoimmune clinical dermatomyositis distribution dm lesions myopathy myositis pm polymyositis primarycare pustular scleroderma secondary syphilis systemicsclerosis
Diffuse Systemic Sclerosis (Scleroderma) - Pulmonary Fibrosis -> Crackles, Abnormal CXR - Pulmonary Hypertension, Right Heart
nodules under skin ... ) - Finger/hand ... and bushy - Finger ... pathophysiology #signs ... #symptoms #diagnosis
Secondary Syphilis Rash Secondary syphilis is the most contagious of all the stages of this disease, and
Skin rash and malaise ... commonly characterize ... The signs and symptoms ... the palms of the hands ... #Photo #Dermatology
Pustular Skin Lesions - Differential Diagnosis Framework What are pustules? • Pustules < 5-10 mm + pus • Material
- Differential Diagnosis ... Irregular pustules on hands ... Burrows between fingers ... Generalized itchy rash ... #Dermatology
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
processes occur in the skin ... dorsum of the hands ... -> Heliotrope Rash ... regeneration, diffuse ... Pathophysiology #Signs
Common Dermatological Conditions - Distribution and Morphology • Acne vulgaris - Face, upper back, chest -
associated with signs ... soles, sides of fingers ... pruritus (e.g., fingers ... axillae, between fingers ... #diagnosis #skin
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... Nodosa: • PAN most commonly ... , mucositis • Rash ... • Progressive symptoms
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
) • Anti-Mi2 (skin ... : • Gottron rash ... ) • Shawl sign ... flexors, quadriceps, finger ... • Mechanic's hands
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