11 results
Manifestations of IgG4-related disease by organ system.
 The most common primary disease features are indicated in
disease by organ system ... are indicated in bold ... Disease #Organs #Systems ... #Diagnosis #Hematology ... #Signs #Symptoms
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
and duration of symptoms ... within one hour or longer ... angioedema Other symptoms ... #Urticaria #diagnosis ... #rheumatology #
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
nose, ears, or fingers ... Test: Donath-Landsteiner ... test #cold # ... hemolytic #anemia #hematology ... #diagnosis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome Systemic ... matter, spinal cord ... meningitis), MCC CNS symptoms ... #management #signs ... #symptoms #rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
signs/sx of inflammation ... the “Chewing gum test ... them, but urgent rheumatology ... GCA #Temporal #Signs ... #Symptoms #Diagnosis
Nail Pathologies - Findings in or Near Nails

Paronychia 

A superficial infection of the proximal and lateral
Systemic causes ... illness, trauma, and cold ... Abnormal #Pathology #Diagnosis ... #Clinical #Signs ... #PhysicalExam #
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... Symptoms (Sx) in ... purpura: strong sign ... retinopathy Lab Tests ... #rheumatology #
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
Rheumatologic ... acute pulmonary, systemic ... the circulatory system ... that exists as a mold ... scalp, vagina, fingers
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
rendering the immune system ... adults in the west ... with no early symptoms ... Physical Exam/Signs ... ’s CLL Scoring system
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
- Differential Diagnosis ... Symptoms (SX) in ... purpura: Strong sign ... • Progressive symptoms ... #Rheumatology