19 results
CREST Syndrome: Pathogenesis and Clinical Findings

CALCINOSIS (BB-sized, hard nodules in fingers)
RAYNAUD'S Phenomenon
ESOPHAGEAL DYSMOTILITY
SCLERODACTYLY (thickening and tightening
Clinical Findings ... nodules in fingers ... tightening of skin ... #Diagnosis #Signs ... #Symptoms
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Clinical Findings ... enzyme 21-OHase causes ... Signs/Symptoms/Complications ... cold & mottled skin ... #pathophysiology
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
clinical findings ... lesions in the inner ... #Retinopathy #pathophysiology ... ophthalmology #diagnosis #signs ... #symptoms #complications
Raynaud’s Phenomenon: Pathogenesis and clinical findings
 • Finger pulp atrophy
 • Tissue ischemia/infarction -> Digital ulcerations
clinical findings ... • Finger pulp ... discoloration of the skin ... Raynauds #Phenomenon #pathophysiology ... #signs #symptoms
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
clinical findings ... processes occur in the skin ... Muscle necrosis, fiber ... PM #Diagnosis #Pathophysiology ... #Signs #Symptoms
Cullen's sign. Lipase 1,781. Bruising in the skin around the umbilicus. This sign is named after
Bruising in the skin ... conditions that cause ... Pathophysiology: ... pregnancy, or other causes ... onset of other symptoms
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... renal failure Clinical ... nodes: 13-15%, skin ... Diagnosis #Management #Signs ... #Symptoms
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Heat Stroke - Differential ... Collapse: • Pathophysiology ... → Syncope • Signs ... /Symptoms: - Lightheadedness ... #diagnosis #causes
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... failure PBC Signs ... and Symptoms: ... Examination: • Skin
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Skin rash and malaise ... The signs and symptoms ... the palms of the hands ... resembling rashes caused ... #Photo #Dermatology