82 results
Characteristic clinical manifestations of Down syndrome 
 
Typical craniofacial appearance 
 • Round face and flat
Characteristic clinical ... manifestations of Down syndrome ... incurved fifth finger ... #Downs #Syndrome ... #PhysicalExam #
Patterns of Diseases on MRI FLAIR - Differential Diagnosis
ADEM, Adreno-leukodystrophy, CADASIL, CNS, Lymphoma, High-Grade Glioma, HIV
on MRI FLAIR - Differential ... Diagnosis ADEM ... Disease, Susac Syndrome ... Leukoencephalopathy, Vascular ... #clinical
Nail diseases and disorders.
 - Spoon Nails (Koilonychia)
 - Pitting of Nails
 - Beau's Lines
 -
Leukonychia (white spots ... ) #Diagnosis # ... Fingernail #Disorders #Differential ... Leukonychia #Table #Clinical ... #PhysicalExam
Differential diagnoses for the neuro-ophthalmologic finding of diplopia.
Neoplastic: 
 • Intraorbital meningioma 
 • Pituitary adenoma
Differential diagnoses ... Carcinomatosis Vascular ... GBS • Miller-Fisher ... syndrome • Orbital ... #Diagnosis #Causes
Important Causes of Diplopia 
TIER 1-CRITICAL
Basilar artery thrombosis, Botulism, Basilar meningitis, Aneurysmn
TIER 2-EMERGENT:
Vertebral dissection, Myasthenia gravis,
Diplopia TIER 1-CRITICAL ... tumor, Miller-Fisher ... syndrome, Multiple ... mass #Diplopia #differential ... #diagnosis #ophthalmology
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
Pathogenesis and clinical ... narrowing and vascular ... -> Cotton-wool Spots ... -> Elschnig's Spots ... ophthalmology #diagnosis
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Shock - Differential ... Diagnosis Framework ... Abdominal compartment syndrome ... , Vascular compression ... algorithm #treatment #management
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
meningococcal, H1N1) Clinical ... Guillain-Barre Clinical ... • Weakness: Starts ... Guillain-Barre Diagnosis ... #diagnosis #management
Mechanisms of Pain
Mixed - Nociceptive/Neuropathic
Nociceptive - Tissue Damage
 - Visceral - (From organ/cavity lining) Poorly localized,
Well-localized, sharp, short ... well-localized, dull, longer ... regional pain syndrome ... Mechanisms #Neurology #Differential ... #Diagnosis #Algorithm
Diabetic Retinopathy: Pathogenesis and clinical findings

Mild Non-proliferative DR
 • Outpouchings of the weakened capillary walls or
Pathogenesis and clinical ... -> Cotton-wool spots ... Focal areas of saccular ... of VEGF causing fine ... ophthalmology #diagnosis