28 results
Characteristic clinical manifestations of Down syndrome 
 
Typical craniofacial appearance 
 • Round face and flat
manifestations of Down syndrome ... • Brushfield spots ... incurved fifth finger ... #Downs #Syndrome ... #PhysicalExam #
Gerstmann Syndrome
1) Finger agnosia - Inability to name their own fingers, affecting both sides
2) Right-left confusion
Gerstmann Syndrome ... 1) Finger agnosia ... name their own fingers ... - Inability to differentiate ... patient is still able
Nail diseases and disorders.
 - Spoon Nails (Koilonychia)
 - Pitting of Nails
 - Beau's Lines
 -
Leukonychia (white spots ... Fingernail #Disorders #Differential ... #Leukonychia #Table ... #Clinical #PhysicalExam
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
Short Stature - ... Differential Diagnosis ... • Turner Syndrome ... Panhypopituitarism Treatment ... #ShortStature #Differential
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... • Weakness: Starts ... death Miller Fisher ... Treatment: • Plasmapheresis ... diagnosis #management #treatment
Mechanisms of Pain
Mixed - Nociceptive/Neuropathic
Nociceptive - Tissue Damage
 - Visceral - (From organ/cavity lining) Poorly localized,
Well-localized, sharp, short ... well-localized, dull, longer ... regional pain syndrome ... Mechanisms #Neurology #Differential
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
thyroid, Sjogren syndrome ... “dropping head syndrome ... life-threatening Differential ... - Kearns-Sayre syndrome ... stimulation - Single fiber
Nail Pathologies - Findings in or Near Nails

Paronychia 

A superficial infection of the proximal and lateral
White Spots (Leukonychia ... nonuniform white spots ... Spots in the pattern ... seen in Reiter's syndrome ... Clinical #Signs #PhysicalExam
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... - Compartment syndrome ... fluid/Lactated ringers ... per day until stable ... Rhabdomyolysis #Differential
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Rhabdomyolysis - Differential ... iniury, Compartment syndrome ... Neuroleptic malignant syndrome ... oxidative iniury Treatment ... per day until stable