11 results
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... Vascular Causes ... disease - If ALP ... Tests of synthetic function ... #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
smear, HIV/HCV testing ... country), thyroid function ... not required in all ... or if a primary hematologic ... #Workup #hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
nephrocalcinosis • CPPD ... severe mobility/functional ... adult population: also ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Weakness • Spinal Cord ... Motor Nerves: ALS ... Neuromuscular junction ... poisoning, Scorpion sting
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... box indicates all ... decision for repeat testing ... ALP, alkaline phosphatase ... ; ALT, alanine aminotransferase
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Algorithm regarding ... elevated, HFE gene testing ... Step 3: All patients ... ALT, alanine aminotransferase ... hemochromatosis #algorithm
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Lateral Sclerosis (ALS ... ) Summary ALS: combination ... disrupt cellular function ... (1) limb-onset ALS ... - Further testing
Hypophosphatemia and Hypoxia - Pathophysiology

↓ Phosphate leads to ↓ red cell 2,3-DPG and a  reduction
impacts respiratory function ... pressure increased in all ... is a cause of refractory ... phosphorus is seen in COPD ... patients with COPD
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
syndrome): - Hematologic ... Treat underlying cause ... replacement Cord ... radiology for possible stenting ... AML (~20 %) and APL
Evaluation of Recurrent Falls

Core Concept:
Maintaining an upright posture requires the integrated function of multiple systems.
Disruption in
the integrated function ... ) - Spinal cord ... neuron disease (ALS ... weakness, muscle wasting ... fear of falling, functional