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diagnosis anemia hemolytic agglutinin causes cold deficiency disease enzymes extravascular glomerulonephritis hemolysis hepatology intravascular lfts liver progressive rapidly rheumatology rpgn
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Diagnosis Algorithm ... Drug-induced AIHA - Abnormal ... perfringens - Complement-Mediated ... #Diagnosis #Algorithm ... #Causes #Hematology
Complement Deficiency Testing Algorithm • Normal CH50 and AH50 AND High suspicion for complement deficiency •
Complement Deficiency ... Testing Algorithm ... suspicion for complement ... #Deficiency #Testing ... #Algorithm #hematology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Idiopathic • Normal ... Complement: IgA ... Glomerulonephritis #Vasculitis #differential ... #diagnosis #algorithm ... #rheumatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Positive Coombs testing ... post infectious setting ... younger pts) Differential ... temperatures by fixing complement ... hemolytic #anemia #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Diagnosis Algorithm ... Agglutination - Cold ... #workup #hematology ... #testing
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... tests algorithm ... decision for repeat testing ... #Algorithm #Hepatology ... Liver #Enzymes #Differential
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