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diagnosis anemia differential hematology causes hemolysis intravascular agglutinin aiha cold disease workup
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Diagnosis Algorithm ... Extravascular ... Warm AIHA • Cold ... AIHA • Alloimmune ... Differential #Diagnosis #Algorithm
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Immune-mediated: - Autoimmune ... idiopathic) - Autoimmune ... (AIHA)"Cold" (usually ... (e.g. primary cold ... #Hemolytic #Intravascular
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral infection, autoimmune ... Positive Coombs testing ... post infectious setting ... CLL (older) • Autoimmune ... the RBCs causing intravascular
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... Agglutination - Cold ... elliptocytosis, autoimmune ... Differential #Diagnosis #Algorithm ... workup #hematology #testing
Autoimmune Hemolytic Anemia (AIHA) WARM AHA - Primary - Idiopathics - Secondary Infectious • Viral- HIV, EBV, HCV, HEV •
Autoimmune Hemolytic ... Non-Hodgkin Lymphoma Autoimmune ... alpha-methyldopa COLD ... #Hemolytic #Anemia ... #Differential #Algorithm
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