88 results
IDSA Treatment Recommendations for Cryptococcal Meningoencephalitis in Human Immunodeficiency Virus Infected Individuals
Induction therapy:
 • AmBd (0.7–1.0
Recommendations for Cryptococcal ... • AmBd plus fluconazole ... • Fluconazole ... week) >1 year #Cryptococcal ... management #meningitis #cryptococcus
IDSA Treatment Recommendations for Cryptococcal Meningoencephalitis in Transplant Recipients
Induction therapy:
 • liposomal AmB (3–4 mg/kg per
Recommendations for Cryptococcal ... Consolidation therapy: fluconazole ... Maintenance therapy: fluconazole ... year B-III #Cryptococcal ... management #meningitis #cryptococcus
Spectrum of activity for systemic antifungal agents
Antifungals: 5FC, flucytosine; AMB, amphotericin B; ANI, anidulafungin; CAS, caspofungin;
caspofungin; FLU, fluconazole ... Aspergillus fumigatus, Cryptococcus
Antifungal Echinocandins  - Antibiotics Class Overview

Mechanism: Inhibit glucan synthesis in fungal cell wall by blocking
species including Fluconazole-resistant ... lack activity vs Cryptococcus
IDSA Recommendations for Preventing and Treating Cryptococcosis in HIV-AIDS
Treatment for cryptococcosis consists of 3 phases: induction,
Preferred Regimen: • Fluconazole ... Preferred Regimen: • Fluconazole ... Cryptococcosis #Cryptococcus
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
Treatment: • Fluconazole ... CRYPTOCOCCUS ... level, presence of cryptococcal ... CSF and serum Cryptococcal ... Treatment: • Fluconazole
Cryptococcal meningitis on T2 MRI
30 M from sub-Saharan Africa presents w/ progressive Headache x1 mo, +neck
Cryptococcal meningitis ... Cryptococcal meningitis ... with high-dose fluconazole ... lower dose of fluconazole ... plus high-dose fluconazole
Important Fungal Stains
Mycology Lab:
 • Calcofluor white - Fluorochrome that binds glucans and chitin in fungal
polysaccharide capsule of Cryptococcus ... detection for cryptococcal ... mucopolysaccharide capsule of Cryptococcus ... cell walls of Cyptococcus
Antifungal Azoles - Antibiotics Class Overview

Mechanism:  inhibit ergosterol synthesis (important component of fungal cell membranes)
- Only Fluconazole ... Fluconazole(PO or ... Azoles #Antifungal #Fluconazole
Cryptococcus neoformans Meningoencephalitis- The opening pressure on lumbar puncture was 29 cm of water (reference range,
Cryptococcus neoformans ... The cryptococcal ... CSF culture grew Cryptococcus ... clinical #NEJM #Cryptococcus