5985 results
Workup for Vitamin B12 and Folate Deficiency

#Workup #VitaminB12 #Folate #Deficiency #FolicAcid #Diagnosis #Macrocytosis #MacrocyticAnemia #Algorithm
Vitamin B12 and Folate ... Workup #VitaminB12 #Folate ... Deficiency #FolicAcid #Diagnosis
Etiologies of Folate Deficiency
 • Decreased dietary intake - uncommon in this era
 • Increased requirements
Etiologies of Folate ... underlying mild folate ... consumption of folate ... In addition, folate ... #differential #diagnosis
Methylmalonic Acid and Homocysteine Levels in Vitamin B12 and Folate Deficiency
 • B12 Deficiency: MMA elevated,
Vitamin B12 and Folate ... Homocysteine elevated • Folate ... Homocysteine #B12 #MMA #folate ... deficiency #VitaminB12 #diagnosis
Diagnosing Vitamin B12 and/or Folate Deficiency

It turns out that simply measuring serum levels of B12 or
Diagnosing Vitamin ... B12 and/or Folate ... levels of B12 or folate ... inadequate to diagnosis ... #Deficiency #Diagnosis
Folate Deficiency - Causes of Decreased Folic Acid
↓ Intake: Diet, Age, Alcohol
↑ Demand: Pregnancy, Infancy, Hemolysis,
Folate Deficiency ... @drkeithsiau #Folate ... #differential #diagnosis
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
- Differential Diagnosis ... Deficiency • Folate ... Deficiency • Folate ... #Differential #Diagnosis
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
Anemia • 812, Folate ... #differential #diagnosis
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
Underproduction Diagnostic ... Vitamin B12 and/or folate ... Algorithm #hematology #diagnosis
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
- Differential Diagnosis ... deficiency: • B12/folate ... #Differential #Diagnosis
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
- Differential Diagnosis ... Neutrophils - Low RBC Folate ... Rule out B12 and Folate ... #Differential #Diagnosis