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diagnosis differential deficiency hematology algorithm folate causes folicacid homocysteine management mma neurology pancytopenia aafp ascorbicacid b1 b12 bariatric bypass comparison
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
of macrocytic anemia ... elevated, but anemia ... but undiagnosed, folate ... megaloblastic anemia ... #VitaminB12 #Folate
Diagnosing Vitamin B12 and/or Folate Deficiency It turns out that simply measuring serum levels of B12 or
Vitamin B12 and/or Folate ... levels of B12 or folate ... Since folate is ... #VitaminB12 #Folate ... Deficiency #Diagnosis #Nutrition
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Toxins • Aplastic Anemia ... Myelodysplasia Nutritional ... deficiency: • B12/folate
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
E - Haemolytic anaemia ... paraesthesiae • Folate ... - Anaemia, neural ... Vitamin B12 - Anaemia ... signs #symptoms #nutrition
Micronutrient Deficiencies After Gastric Bypass Fat-Soluble Vitamins: • Vitamin A - Night/complete blindness, xeropthalmia (pathologic dryness of
cardiomyopathy) • Folate ... - Macrocytic anemia ... B12 - Macrocytic anemia ... Minerals: • Iron - Anemia ... Bypass #vitamin #nutrition
Etiologies of Folate Deficiency • Decreased dietary intake - uncommon in this era • Increased requirements
Etiologies of Folate ... have hemolytic anemia ... underlying mild folate ... In addition, folate ... diagnosis #hematology #nutrition
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
deficiency • Fanconi’s anemia ... Antibody-mediated hemolysis Nutritional ... Vitamin B12 • Folate
Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency Wernicke's encephalopathy is a neurological condition due to longstanding
and retrograde amnesia ... #vitaminB1 #B1 # ... diagnosis #comparison #neurology
Etiologies of Peripheral Neuropathy • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism • Medication-induced: ART, Antibiotics,
• Metabolic / Nutritional ... DiabetesB12 deficiency, Uremia ... diagnosis #causes #neurology
Scurvy (Vitamin C Deficiency) - Diagnosis and Management Vitamin C is required for hydroxylation of proline residues
persons with poor nutrition ... breath, wasting, anemia ... Loss of teeth Anemia ... lead to iron and folate ... Pathophysiology #Nutrition
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