30 results
Methylmalonic Acid and Homocysteine Levels in Vitamin B12 and Folate Deficiency
 • B12 Deficiency: MMA elevated,
Vitamin B12 and Folate ... Homocysteine elevated • Folate ... Homocysteine #B12 #MMA #folate ... #deficiency #VitaminB12 ... #diagnosis #hematology
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Infiltration: • Hematologic ... and non-hematologic ... Toxins • Aplastic Anemia ... Myelodysplasia Nutritional ... deficiency: • B12/folate
Diagnosing Vitamin B12 and/or Folate Deficiency

It turns out that simply measuring serum levels of B12 or
Vitamin B12 and/or Folate ... levels of B12 or folate ... #VitaminB12 #Folate ... Deficiency #Diagnosis #Nutrition ... #Hematology #ComparisonTable
Etiologies of Folate Deficiency
 • Decreased dietary intake - uncommon in this era
 • Increased requirements
Etiologies of Folate ... have hemolytic anemia ... In addition, folate ... differential #diagnosis #hematology ... #nutrition
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
Hypoproliferative Macrocytic Anemia ... • 812, Folate ... #Macrocytic #Anemia ... diagnosis #algorithm #hematology
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
Anemia - Underproduction ... Iron deficiency anemia ... - Anemia of chronic ... Vitamin B12 and/or folate ... Underproduction #Algorithm #hematology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
deficiency • Fanconi’s anemia ... Antibody-mediated hemolysis Nutritional ... Vitamin B12 • Folate ... Differential #Diagnosis #Hematology
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
of macrocytic anemia ... elevated, but anemia ... but undiagnosed, folate ... megaloblastic anemia ... #VitaminB12 #Folate
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Deficiency • Folate ... Deficiency • Folate ... Algorithm #Causes #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Neutrophils - Low RBC Folate ... • Pernicious Anemia ... Rule out B12 and Folate ... Algorithm #Causes #Hematology