8 results
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
and non-hematologic ... Toxins • Aplastic Anemia ... Myelodysplasia Nutritional ... deficiency: • B12/folate ... /combined deficiencies
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
deficiency • Fanconi’s anemia ... Antibody-mediated hemolysis Nutritional ... Deficiencies: ... Vitamin B12 • Folate ... Differential #Diagnosis #Hematology
Nutrient Deficiencies and Supplementation Post Gastric Bypass Surgery
Nutrient Deficiencies:
 • Most frequent in the malabsorptive surgeries
common are Vit D, folate ... behaviors and alcohol Nutritional ... Bl, B12, Vit D, Folate ... Gastroenterology and Hepatology ... gastroenterology #nutrition
Diagnosing Vitamin B12 and/or Folate Deficiency

It turns out that simply measuring serum levels of B12 or
Vitamin B12 and/or Folate ... levels of B12 or folate ... #VitaminB12 #Folate ... Deficiency #Diagnosis #Nutrition ... #Hematology #ComparisonTable
Etiologies of Folate Deficiency
 • Decreased dietary intake - uncommon in this era
 • Increased requirements
Etiologies of Folate ... have hemolytic anemia ... In addition, folate ... differential #diagnosis #hematology ... #nutrition
Micronutrient Deficiencies After Gastric Bypass
Fat-Soluble Vitamins:
 • Vitamin A - Night/complete blindness, xeropthalmia (pathologic dryness of
Micronutrient Deficiencies ... cardiomyopathy) • Folate ... - Macrocytic anemia ... uw_IMresidency #nutrient #Deficiencies ... Bypass #vitamin #nutrition
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
Index < 2: • Anemia ... inflammation • Nutrient deficiencies ... , Vitamin B12, Folate ... • Hormone deficiencies ... Production #Index #hematology
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
persons with poor nutrition ... breath, wasting, anemia ... Loss of teeth Anemia ... lead to iron and folate ... deficiencies