9 results
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Infiltration: • Hematologic ... and non-hematologic ... Toxins • Aplastic Anemia ... Myelodysplasia Nutritional ... deficiency: • B12/folate
Diagnosing Vitamin B12 and/or Folate Deficiency

It turns out that simply measuring serum levels of B12 or
Vitamin B12 and/or Folate ... levels of B12 or folate ... #VitaminB12 #Folate ... Deficiency #Diagnosis #Nutrition ... #Hematology #ComparisonTable
Etiologies of Folate Deficiency
 • Decreased dietary intake - uncommon in this era
 • Increased requirements
Etiologies of Folate ... have hemolytic anemia ... In addition, folate ... differential #diagnosis #hematology ... #nutrition
Nutrient Deficiencies and Supplementation Post Gastric Bypass Surgery
Nutrient Deficiencies:
 • Most frequent in the malabsorptive surgeries
Supplementation Post Gastric ... common are Vit D, folate ... Bl, B12, Vit D, Folate ... Supplementation #Gastric ... gastroenterology #nutrition
Micronutrient Deficiencies After Gastric Bypass
Fat-Soluble Vitamins:
 • Vitamin A - Night/complete blindness, xeropthalmia (pathologic dryness of
Deficiencies After Gastric ... cardiomyopathy) • Folate ... - Macrocytic anemia ... #Deficiencies #Gastric ... Bypass #vitamin #nutrition
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
deficiency • Fanconi’s anemia ... Antibody-mediated hemolysis Nutritional ... Vitamin B12 • Folate ... Differential #Diagnosis #Hematology
Causes of Anemia in Cirrhosis - Differential Diagnosis Framework
LOW RETIC INDEX - ↓ PRODUCTION
 • Vitamin
Causes of Anemia ... B12 deficiency, Folate ... bleed, esophageal, gastric ... Hemorrhoidal bleed, Gastric ... Differential #Diagnosis #Hepatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
childhood and late ... Most common - gastric ... • Atypical microorganisms ... autoimmune hemolytic anemia ... hypogammaglobulinemia #immunology #hematology
Etiologies of Vitamin B12 Deficiency
 • Inadequate intake - Rare but seen in very strict vegans
• Abnormal gastric ... autoantibodies (pernicious anemia ... Bloodman #B12 #VitaminB12 ... differential #diagnosis #hematology ... #nutrition