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Acid Base Disorders - Formulas for appropriate metabolic and respiratory compensation

- Dr Amith Sreedharan - Consultant
Acid Base Disorders ... - Formulas for ... Metabolic #Acidosis #Alkalosis ... Formula #Winters ... Diagnosis #Nephrology #AcidBase
Summary of metabolic compensation for respiratory acid-base disorders
#Diagnosis #Nephro #Respiratory #Acidosis #Alkalosis #Metabolic #Compensation #Formulas #Curbsiders
Summary of metabolic compensation ... respiratory acid-base ... Respiratory #Acidosis #Alkalosis ... #Metabolic #Compensation ... #Formulas #Curbsiders
Prediction of Compensatory Responses on Simple Acid-Base Disturbances

#acidbase #compensation #metabolic #respiratory #diagnosis #calculations #formulas #acidosis #alkalosis
on Simple Acid-Base ... Disturbances #acidbase ... #compensation # ... #calculations #formulas ... #acidosis #alkalosis
Acid-Base Disorders - Differential Diagnosis Algorithm
Acidemia (pH < 7.35)
 • Metabolic Acidosis (HCO3 < 24mmol/L) CO2
Acid-Base Disorders ... Differential Diagnosis Algorithm ... • Metabolic Alkalosis ... < 35 mmHg) #AcidBase ... #Causes #Compensation
Acid-Base Disorders - Expected Compensation Equations

Metabolic Acidosis:
 • pCO2 = 1.5 x HCO3 + 8 ±
Acid-Base Disorders ... - Expected Compensation ... ± 2 (Winter’s formula ... #AcidBase #Disorders ... #Compensation #
Approach to Acid Base Disorders - Evaluation and Differential Diagnosis
1) Start with the Anion Gap (AG).
2)
Approach to Acid Base ... more acidotic or alkalotic ... than expected based ... the appropriate compensation ... done by using formulas
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Acid Base Disorders ... Step 3 - Compensation ... • Metabolic compensation ... MDaniyalHashmi1 #AcidBase ... bloodgas #Acid #Base
USMLE Epidemiology and Biostatistics Summary
Meta-Analysis: pools data from several studies (greater power), limited by quality/bias of
Case Control ( ... prove causation Case ... NPV Odds ratio (case ... , 0 = no correlation ... Biostatistics #formulas