Acid-Base Disorders - Expected Compensation Equations Metabolic Acidosis: • pCO2 = 1.5 x HCO3 + 8 ± 2 (Winter’s formula) or • ∆ HCO3 ↓ 1 → ∆ pCO2 ↓ 1.2 Metabolic Alkalosis: • pCO2 = 0.7 x (HCO3 - 24) + 40 ± 5 or • ∆ HCO3 ↑ 1 → ∆ pCO2 ↑ 0.7 Respiratory Acidosis: • Acute: ∆ pCO2 ↑ 10 → ∆ HCO3 ↑ 1 • Chronic: ∆ pCO2 ↑ 10 → ∆ HCO3 ↑ 3 Respiratory Alkalosis: • Acute: ∆ pCO2 ↓ 10 → ∆ HCO3 ↓ 2 • Chronic: ∆ pCO2 ↓ 10 → ∆ HCO3 ↓ 4 #Acid #Base #AcidBase #Disorders #Compensation #Metabolic #Respiratory #Acidosis #Alkalosis
