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Acid Base Disorders - Formulas for appropriate metabolic and respiratory compensation

- Dr Amith Sreedharan - Consultant
Acid Base Disorders ... - Formulas for ... metabolic and respiratory ... Care Medicine #Respiratory ... #Compensation #Formula
Summary of metabolic compensation for respiratory acid-base disorders
#Diagnosis #Nephro #Respiratory #Acidosis #Alkalosis #Metabolic #Compensation #Formulas #Curbsiders
compensation for respiratory ... acid-base disorders ... Diagnosis #Nephro #Respiratory ... #Compensation #Formulas
Prediction of Compensatory Responses on Simple Acid-Base Disturbances

#acidbase #compensation #metabolic #respiratory #diagnosis #calculations #formulas #acidosis #alkalosis
on Simple Acid-Base ... compensation #metabolic #respiratory ... #calculations #formulas
Approach to Acid Base Disorders - Evaluation and Differential Diagnosis
1) Start with the Anion Gap (AG).
2)
Approach to Acid Base ... than expected based ... done by using formulas ... retention • Respiratory ... Ventilation • Respiratory
Acid-Base Disorders - Differential Diagnosis Algorithm
Acidemia (pH < 7.35)
 • Metabolic Acidosis (HCO3 < 24mmol/L) CO2
Acid-Base Disorders ... Differential Diagnosis Algorithm ... HCO3 12:10 • Respiratory ... HCO3 7:10 • Respiratory ... #Causes #Compensation
Sensitivity is the proportion of truly diseased persons in the screened population who are identified as
correctly diagnose a case ... that any given case ... implies being able ... #Calculation #Table ... #PPV #NPV #Formulas
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Acid-Base Disorders - Expected Compensation Equations

Metabolic Acidosis:
 • pCO2 = 1.5 x HCO3 + 8 ±
Acid-Base Disorders ... ± 2 (Winter’s formula ... pCO2 ↑ 0.7 Respiratory ... ∆ HCO3 ↑ 3 Respiratory ... ↓ 4 #Acid #Base
Table 1. Equations for estimated glomerular filtration rate (eGFR) in adults based on serum creatinine concentration*.
#Diagnosis
Table 1. ... eGFR) in adults based ... #Calculation #Formulas
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... normal volume-based ... algorithm Urine ... differential #diagnosis #table
USMLE Epidemiology and Biostatistics Summary
Meta-Analysis: pools data from several studies (greater power), limited by quality/bias of
Proves cause-effect ... Case Control ( ... prove causation Case ... NPV Odds ratio (case ... Biostatistics #formulas