17 results
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
ALP - Biliary ... Transaminase, ALP ... / ULN ALT) / (ALP ... / ULN ALP) ... #FunctionTest #
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Differential Diagnosis Algorithm ... or AST > ALP): ... Wilsons, Pregnancy - AFLP ... Cholestatic Pattern (ALP
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
phos/ULN ALP) ... specificity to elevated ALP ... GGT/5-NT: ↑ • ALP ... - ALP is from extrahepatic ... normal AST/ALT
Pulmonary Function Tests (PFTs) - Interpretation Algorithm
 • Normal
 • Pulmonary Hypertension, Anemia, Carboxyhemoglobinemia
 • Chest
Interpretation Algorithm ... • Normal • ... #Pulmonary #FunctionTests ... Interpretation #Algorithm
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
specificity to elevated ALP ... augment synthesis of ALP ... disease - If ALP ... function may be abnormal ... hemolysis) • ALP
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Alkaline Phosphatase (ALP ... ALP: - Enzymes ... - Increased ALP ... Surgical consult ALP ... #Phosphatase #ALP
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
to 10-20-fold elevation ... Hepatic imaging: Normal ... to 10-20-fold elevation ... of Pregnancy (AFLP ... diagnosis #icp #HELLP #AFLP
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Differential Diagnosis Algorithm ... • Pregnancy - AFLP ... disease US — Normal ... Differential #Diagnosis #Algorithm
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... tests algorithm ... magnitude of enzyme elevation ... ALP, alkaline phosphatase ... #Algorithm #Hepatology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
in 1923 Low ALP ... 1948 by Rathbun ALP ... synthesized in: liver ... eliminated • Elevation ... phosphate &/or • Elevation