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differential hematology aafp dm2 false folicacid hba1c hgba1c homocysteine increase laboratory macrocytic macrocytosis mma reduction testing thromboticthrombocytopenicpurpura ttp vitaminb12
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False Elevation ... Iron, B-12, or folate ... blood loss • Hemolytic ... anemia • Splenomegaly ... #Decrease #Diagnosis
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
Algorithm for the ... Hemorrhage or hemolysis ... also causes an elevation ... #Diagnosis #Macrocytosis ... #Workup #AAFP
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Algorithm • Sickle ... without platelet decrease ... #Diagnosis #Algorithm ... #workup #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
activity is the diagnostic ... result in severe anemia ... anemia Indirect ... Mild-to-moderate elevation ... #Workup #Hematology
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