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diagnosis differential causes classification hematology acidosis approach dm2 false hba1c hgba1c lactate lactic reduction thromboticthrombocytopenicpurpura ttp typea typeb workup
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
== Decreased RBC ... Iron, B-12, or folate ... Reduction == Increase ... End-stage renal disease ... #Increase #Decrease
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... combination of: Decreased ... Deficiency • B12/Folate ... Disease • Marrow ... Differential #Diagnosis #Algorithm
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... hallmark for the disease ... Mild-to-moderate decrease ... result in severe anemia ... Mild-to-moderate elevation
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
presentations and disease ... - assess other laboratory ... Circulatory System • Increased ... muscle use • Decreased ... 30mmHg) - Severe anemia
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