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diagnosis differential hematology aafp approach causes classification dm2 false hba1c hgba1c homocysteine laboratory macrocytic macrocytosis mma nutrition reduction vitaminb12 workup
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Iron, B-12, or folate ... deficiency • ... Reduction == Increase ... HgbA1c #Laboratory #Increase ... #Decrease #Diagnosis
Etiologies of Folate Deficiency • Decreased dietary intake - uncommon in this era • Increased requirements
Deficiency • Decreased ... in this era • Increased ... have hemolytic anemia ... anticonvulsants lead to increase ... #deficiency #FolicAcid
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... Reticulocytes • Iron Deficiency ... • B12/Folate ... Deficiency • Aplastic ... Differential #Diagnosis #Algorithm
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
Algorithm for the ... also causes an elevation ... but undiagnosed, folate ... #VitaminB12 #Folate ... #FolicAcid #MMA
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