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diagnosis management hepatology liver rheumatology causes dermatomyositis lfts nephrology pathophysiology rhabdomyolysis treatment abnormal acidosis aflp algorithm antimda5 antimda5dm callus cardiology
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Function Test (LFTs) Elevation ... SinaiBmoreIMRes #Liver #FunctionTest ... #LFTs #Elevation
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
Creatine Kinase ... Levels Acute CK Elevation ... immobility • Critical ... Kumfer @AnnKumfer #Creatine ... #Elevated #CK #differential
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
weeks • Typical clinical ... to 10-20-fold elevation ... post-partum • Typical clinical ... to 10-20-fold elevation ... hepatitis #comparison #differential
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Pathogenesis and clinical ... cardiomyopathy - Elevation ... levels in serum: Creatinine
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... Presentation: • Elevations ... of serum creatine ... IU/I • SAMS clinical
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Causes of Lactate Elevation ... Lactic Acidosis - Differential ... of lactate as a clinical ... a multitude of clinical ... #Differential #
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
evaluation of the clinical ... /or suspicious clinical ... the remainder, a clinical ... magnitude of enzyme elevation ... Liver #Enzymes #Differential
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
Mild-to-moderate elevation ... WBC count and differential ... casts) BUN and creatinine
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
auricular papules Clinical ... no significant elevation ... without elevated creatine
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... Dermatomyositis Clinical ... ULN • AST/ALT Elevation ... Rhabdomyolysis #Differential
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