9 results
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
for the liver ALP ... - Biliary tree ... Transaminase, ALP ... / ULN ALP) ... SinaiBmoreIMRes #Liver #FunctionTest
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Tests - Differential ... or AST > ALP): ... Wilsons, Pregnancy - AFLP ... Cholestatic Pattern (ALP ... - CBD stone, Biliary
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Alkaline Phosphatase (ALP ... ) Elevation - Differential ... ALP: - Enzymes ... - Increased ALP ... #Elevation #Differential
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... Diagnosis Algorithm ... GGT/5-NT: ↑ - ALP ... , ALP is from extrahepatic ... #diagnosis #algorithm
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
phos/ULN ALP) ... Cholestasis • ALP ... disease • If ALP ... normal AST/ALT ... chemistry #diagnosis #differential
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Liver Enzymes - Differential ... Diagnosis Algorithm ... • Pregnancy - AFLP ... disease US — Normal ... Duct Stone • Biliary
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
tests algorithm ... magnitude of enzyme elevation ... include extrahepatic biliary ... ALP, alkaline phosphatase ... Liver #Enzymes #Differential
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
to 10-20-fold elevation ... to 10-20-fold elevation ... of Pregnancy (AFLP ... hepatitis #comparison #differential ... diagnosis #icp #HELLP #AFLP
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... & AST normal or ... No extrahepatic biliary ... obstruction • ALP ... bile ducts Differential