12 results
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Function Test (LFTs) Elevation ... for the liver ALP ... Transaminase, ALP ... SinaiBmoreIMRes #Liver #FunctionTest ... #LFTs #Elevation
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Wilsons, Pregnancy - AFLP ... kwburak #LFTs #Elevated ... #Abnormal #Transaminitis
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Mild jaundice, Elevated ... to 10-20-fold elevation ... to 10-20-fold elevation ... of Pregnancy (AFLP ... hepatitis #comparison #differential
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
specificity to elevated ... Bilirubin - +/- elevation ... or amyloid: • Elevation ... of Liver Enzyme Elevation ... chemistry #diagnosis #differential
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... specificity to elevated ... Bilirubin - +/- elevation ... function may be abnormal ... of Liver Enzyme Elevation
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... • Pregnancy - AFLP ... disease US — Normal ... #LiverEnzymes #Differential
Causes of ST Segment Elevation - Differential Diagnosis Framework

STEMI:
 • Upsloping convex STE: "Pardee's sign" +
of ST Segment Elevation ... - Differential ... segment becomes elevated ... of Normal Variant ... #differential #
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Elevated Lactate ... Dehydrogenase (LDH) - Differential ... upon damage • Normal ... Idiosyncratic LDH Elevation ... #differential #
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
levels - Usually normal ... or slightly elevated ... Mild-to-moderate elevation ... WBC count and differential ... or may not be elevated
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... initial response to abnormal ... magnitude of enzyme elevation ... ALP, alkaline phosphatase ... Liver #Enzymes #Differential