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diagnosis hepatology lfts elevated hepatitis transaminitis aflp alkaline alp causes chemistry comparison dehydrogenase disease hematology hemolysis icp injury interpretation laboratory
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
to 10-20-fold elevation ... , no necrosis HELLP ... enzymes, and Low ... to 10-20-fold elevation ... hepatitis #comparison #differential
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
- Differential ... Diagnosis Algorithm ... ALP: - Enzymes ... #Differential # ... Diagnosis #Algorithm
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... Diagnosis Algorithm ... Pregnancy - AFLP, HELLP ... disease US — Normal
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... tests algorithm ... elevation and clinical ... #Liver #Enzymes ... #Differential #
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... • Pregnancy: HELLP ... function may be abnormal ... Enzyme Elevation
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Diagnosis Algorithm ... Pregnancy - AFLP, HELLP ... Transaminitis #Algorithm
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... TTP, HUS, DIC, HELLP ... Defects, Drugs, Liver ... , Spiders - Enzyme ... Blood Smear ↑ abnormal
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Bilirubin - +/- elevation ... - If both are normal ... or amyloid: • Elevation ... Enzyme Elevation ... chemistry #diagnosis #differential
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... a cytoplasmic enzyme ... RBCs, muscle, liver ... red blood cell enzymes ... Idiosyncratic LDH Elevation
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