8 results
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Function Test (LFTs) Elevation ... for the liver ALP ... ) vs Indirect (Hemolytic ... SinaiBmoreIMRes #Liver #FunctionTest ... #LFTs #Elevation
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
, no necrosis HELLP ... Syndrome (Hemolysis ... Elevated Liver enzymes ... hepatitis #comparison #differential ... #AFLP
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... Diagnosis Algorithm ... ALP: - Enzymes ... #Elevation #Differential ... #Diagnosis #Algorithm
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... Diagnosis Algorithm ... • Pregnancy - AFLP ... , HELLP Moderate
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... Diagnosis Algorithm ... • Pregnancy: HELLP ... Source of Liver Enzyme ... Elevation: •
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... Diagnosis Algorithm ... deficiency, Other enzyme ... thrombocytopenia - DIC, TTP, HELLP ... #Anemia #Differential
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Bilirubin - +/- elevation ... or amyloid: • Elevation ... Source of Liver Enzyme ... Elevation: • ... chemistry #diagnosis #differential
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
function tests algorithm ... the magnitude of enzyme ... elevation and clinical ... LFTs #Abnormal #Algorithm ... #Differential #