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diagnosis lactate acidosis causes lactic antimda5 antimda5dm bronchiectasis cardiology classification criticalcare dehydrogenase dermatology dermatomyositis elevated false hba1c hematology hgba1c increase
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False Elevation ... • Asplenia Laboratory ... HbA1c #HgbA1c #Laboratory ... #Diagnosis #DM2 ... #Differential
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... Mild-to-moderate decrease ... Platelet count - Decreased ... Mild-to-moderate elevation ... WBC count and differential
Lactic Acidosis - Differential Diagnosis Framework Type A: Impaired O2 Delivery (DO2) • Decreased O2 Delivery: Hypotension
Lactic Acidosis - Differential ... Impaired O2 Delivery (DO2 ... ) • Decreased ... Pain / Exercise, Fever ... Syndrome, where decreased
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... myocarditis, rheumatic fever ... Idiosyncratic LDH Elevation ... Dehydrogenase #Elevated #differential ... #diagnosis #Laboratory
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Causes of Lactate Elevation ... Lactic Acidosis - Differential ... - assess other laboratory ... muscle use • Decreased ... #Differential #
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
Dermatomyositis • Fever ... 74% of anti-MDA5 DM ... no significant elevation ... ILD worsens Decreased ... lesser extent, DM
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... Muscle swelling - Fever ... ULN • AST/ALT Elevation ... vasoconstriction → decreased ... Rhabdomyolysis #Differential
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
run-down or tired • Fevers ... Superimposed infection - increase ... Bronchoscopy Laboratory ... Bronchiectasis #pulmonary #differential
Palpitations - Differential Diagnosis Framework What? • It is an unpleasant awareness or sensation that the heart is
Palpitations - Differential ... ECG • Limited laboratory ... Electrolyte imbalance • Fever ... tachycardia due to decreased ... Palpitations #Cardiology #Differential
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