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diagnosis rheumatology dermatology acidosis antimda5 antimda5dm bronchiectasis cancer cardiology classification dermatomyositis dm2 emergencies false hba1c hgba1c hyperferritinemia increase infections infectiousdiseases
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... Elevation and Reduction ... • Asplenia Laboratory ... HbA1c #HgbA1c #Laboratory ... Diagnosis #DM2 #Differential
Causes of Hyperferritinemia - Differential Diagnosis Ferritin > 1000 Ferritin is the storage form of iron. Increased hepcidin
- Differential ... Decreased hepcidin ... Hematologic Malignancy ... saturation to differentiate ... extreme ferritin elevation
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... in most cases; ... Mild-to-moderate elevation ... WBC count and differential ... Diagnosis #Workup #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Fragility: • Decreased ... mountain spotted fever ... Vasculopathy #Purpura #Differential ... #Diagnosis #hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Elevation, Lactic ... Acidosis - Differential ... - assess other laboratory ... muscle use • Decreased ... #Differential #
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
Emergencies - Differential ... Diagnosis Framework HEMATOLOGIC ... death Neutropenic Fever ... • Vomiting, decreased ... emergencies #oncology #differential
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
Dermatomyositis • Fever ... no significant elevation ... ILD worsens Decreased ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... Management Summary Causes ... Muscle swelling - Fever ... ULN • AST/ALT Elevation ... vasoconstriction → decreased
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
Chronic inflammation causes ... run-down or tired • Fevers ... Superimposed infection - increase ... Bronchoscopy Laboratory ... Bronchiectasis #pulmonary #differential
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Vasculitis: • Fevers ... artery tenderness - decreased ... tract, and often causes ... #Diagnosis #Rheumatology
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