5 results
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... Mild-to-moderate decrease ... Mild-to-moderate elevation ... WBC count and differential ... Diagnosis #Workup #Hematology
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
or normal) • Elevation ... : Elevated • Decreases ... Scoring #diagnosis #hematology ... #laboratory
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Fragility: • Decreased ... mountain spotted fever ... #Diagnosis #hematology ... #nonpalpable #dermatology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... without platelet decrease ... bartonella (oroya fever ... Hemolytic #Anemia #Differential ... Algorithm #workup #hematology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
Dermatomyositis • Fever ... no significant elevation ... ILD worsens Decreased ... Dermatomyositis #rheumatology ... #dermatology #diagnosis