15 results
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
• Asplenia Laboratory ... Reduction == Increase ... HbA1c #HgbA1c #Laboratory ... #Increase #Decrease ... Diagnosis #DM2 #Differential
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... Mild-to-moderate decrease ... Platelet count - Decreased ... Mild-to-moderate elevation ... WBC count and differential
Laboratory Evaluation of Patients for Thyroid Disease 
Hyperthyroidism:
 • Graves disease - TSH low; free T4
Laboratory Evaluation ... ; decreased radioactive ... sedimentation rate normal; decreased ... Euthyroid sick syndrome ... #hyperthyroid #differential
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Emergencies - Differential ... death Neutropenic Fever ... , hypotension, increased ... • Vomiting, decreased ... emergencies #oncology #differential
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
Lactic Acidosis - Differential ... Delivery (DO2) • Decreased ... • Increased O2 ... Pain / Exercise, Fever ... , where decreased
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... myocarditis, rheumatic fever ... • Tumor lysis syndrome ... Idiosyncratic LDH Elevation ... #diagnosis #Laboratory
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Muscle swelling - Fever ... ULN • AST/ALT Elevation ... vasoconstriction → decreased ... Rhabdomyolysis #Differential
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... - assess other laboratory ... Circulatory System • Increased ... muscle use • Decreased ... - Compartment syndrome
Bronchiectasis - Summary

What?
• Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
run-down or tired • Fevers ... • Mounier-Kuhn syndrome ... Superimposed infection - increase ... Bronchoscopy Laboratory ... Bronchiectasis #pulmonary #differential
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
Acute Retroviral Syndrome ... Acute Retroviral Syndrome ... Headache (45%) • Fever ... - Liver enzyme elevation ... T-cell count can decrease