12 results
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
• Asplenia Laboratory ... Reduction == Increase ... HbA1c #HgbA1c #Laboratory ... #Increase #Decrease ... Diagnosis #DM2 #Differential
Tuberculous Pleural Effusions - Tests and Biomarkers
Age + fever + red blood cells + ADA -
Biomarkers Age + fever ... IFN-y + NAAT - Increase ... #Tuberculosis #Laboratory ... #Testing #diagnosis
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... without platelet decrease ... bartonella (oroya fever ... Hemolytic #Anemia #Differential ... workup #hematology #testing
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... Mild-to-moderate decrease ... Platelet count - Decreased ... Mild-to-moderate elevation ... WBC count and differential
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
Lactic Acidosis - Differential ... Delivery (DO2) • Decreased ... Compartment Syndrome • Increased ... Pain / Exercise, Fever ... separate D-lactate testing
Bronchiectasis - Summary

What?
• Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
run-down or tired • Fevers ... Superimposed infection - increase ... Bronchoscopy Laboratory ... the airway • Treating ... Bronchiectasis #pulmonary #differential
Evaluation of Leukocytosis:
The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages.
Include
neutropenia: typhoid fever ... part automated differential ... Reaction: Transient increase ... D/D leukemia: increases ... Improves after treating
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... - assess other laboratory ... Circulatory System • Increased ... muscle use • Decreased ... #Differential #
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
and should not increase ... BAL GM does not differentiate ... - Sensitivity decreased ... post-2010 almost never ... Frozen ice-pops (in setting
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
- Alkalosis, Increased ... periodic paralysis Decreased ... Intake: - Fasting ... , Heat stroke, Fever ... Hypokalemia #Causes #differential