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acidosis causes lactic classification criticalcare dehydrogenase elevated false hba1c hematology hgba1c increase ldh management nephrology reduction rhabdomyolysis thromboticthrombocytopenicpurpura treatment ttp
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
== Decreased RBC ... • Asplenia Laboratory ... HbA1c #HgbA1c #Laboratory ... #Diagnosis #DM2 ... #Differential
Lactic Acidosis - Differential Diagnosis Framework Type A: Impaired O2 Delivery (DO2) • Decreased O2 Delivery: Hypotension
Lactic Acidosis - Differential ... Impaired O2 Delivery (DO2 ... ) • Decreased ... Pain / Exercise, Fever ... Syndrome, where decreased
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Elevation, Lactic ... Acidosis - Differential ... - assess other laboratory ... muscle use • Decreased ... #Differential #
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... activity is the diagnostic ... Mild-to-moderate elevation ... Serum lactate ... WBC count and differential
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Elevated Lactate ... Diagnosis Framework ... myocarditis, rheumatic fever ... Idiosyncratic LDH Elevation ... #diagnosis #Laboratory
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Diagnosis Framework ... Muscle swelling - Fever ... ULN • AST/ALT Elevation ... vasoconstriction → decreased ... Isotonic fluid/Lactated
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