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diagnosis differential acidosis causes hepatology infectiousdiseases lactic lfts management rheumatology syndrome travel abdominal abnormal abscess activation acute algorithm antimda5 antimda5dm
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... specific for the liver ... #FunctionTest # ... LFTs #Elevation
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Elevation, Lactic ... glucose by the liver ... contribution of liver ... Elevation Type ... Lactic #Acidosis #Elevation
Fever in Returning Travelers from Tropical Regions - Frequent Differential Diagnoses Medical History: • Skin exposure to
amebic abscess of liver ... Jaundice (and/or elevation ... of liver enzymes ... Typhoid, amebic liver ... fluke, amebic liver
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... response to abnormal liver ... derangement of liver ... magnitude of enzyme elevation ... normalised ratio; LDH, lactate
Lactic Acidosis - Differential Diagnosis Framework Type A: Impaired O2 Delivery (DO2) • Decreased O2 Delivery: Hypotension
Pain / Exercise, Fever ... Clearance: Systemic liver ... with negative lactate ... sugars into D-Lactate ... #criticalcare #lactate
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Elevated Lactate ... RBCs, muscle, liver ... myocarditis, rheumatic fever ... Idiosyncratic LDH Elevation ... disease #LDH #Lactate
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... thrombocytopenia • Liver ... Triglycerides • ↑ Lactate
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Muscle swelling - Fever ... ULN • AST/ALT Elevation ... Isotonic fluid/Lactated
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
Dermatomyositis • Fever ... no significant elevation ... disease and ILD • Liver ... Liver biopsies show
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
Headache (45%) • Fever ... Hepatomegaly - Liver ... enzyme elevation ... subset counts ↓ • Liver
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