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diagnosis differential hepatology management algorithm lfts blood hematology infectiousdiseases product reactions transaminitis travel treatment abnormal acute antimda5 antimda5dm bacterial causes
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... specific for the liver ... #FunctionTest # ... LFTs #Elevation
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH ... RBCs, muscle, liver ... and kidney • LDH ... myocarditis, rheumatic fever ... Elevation: •
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Liver Chemistries ... Bilirubin - +/- elevation ... or amyloid: • Elevation ... Enzyme Elevation ... muscle, Kidneys • LDH
Fever in Returning Travelers from Tropical Regions - Frequent Differential Diagnoses Medical History: • Skin exposure to
amebic abscess of liver ... Jaundice (and/or elevation ... of liver enzymes ... Typhoid, amebic liver ... fluke, amebic liver
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Causes of Acute Liver ... Bilirubin - +/- elevation ... Enzyme Elevation ... muscle, kidneys • LDH
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... response to abnormal liver ... derangement of liver ... magnitude of enzyme elevation ... normalised ratio; LDH
Signs and Symptoms of Renal Infarction • Abdominal or flank pain • Leukocytosis • Fever •
Leukocytosis • Fever ... Hematuria • Elevations ... of serum LDH, transaminases
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Muscle swelling - Fever ... ULN • AST/ALT Elevation ... Aldolase ↑ • LDH
Spontaneous Bacterial Peritonitis DIAGNOSTICS Paracentesis: • Calculate absolute PMN count (total WBC x PMN %) • Correct
glucose < 50mg/dL, LDH ... if other signs (fever ... dL and advanced liver
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
Dermatomyositis • Fever ... no significant elevation ... disease and ILD • Liver ... Liver biopsies show
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