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diagnosis differential hepatology hepatitis lfts transaminitis aafp aflp aih alkaline alkphos anemia autoimmune causes chemistry comparison creactiveprotein crp dehydrogenase disease
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... specific for the liver ... #FunctionTest # ... LFTs #Elevation
Algorithm for evaluation of elevated serum alkaline phosphatase. #Algorithm #elevated #alkaline #phosphatase #AlkPhos #Elevation #Diagnosis #workup
Algorithm for evaluation ... of elevated serum ... #Algorithm #elevated ... phosphatase #AlkPhos #Elevation ... #Diagnosis #workup
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Mild jaundice, Elevated ... to 10-20-fold elevation ... Hepatic imaging: Normal ... Syndrome (Hemolysis, Elevated ... to 10-20-fold elevation
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
specificity to elevated ... Bilirubin - +/- elevation ... - If both are normal ... or amyloid: • Elevation ... Enzyme Elevation
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... specificity to elevated ... Bilirubin - +/- elevation ... function may be abnormal ... Enzyme Elevation
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
Algorithm for the ... reticulocyte count is elevated ... also causes an elevation ... of the initial work-up ... #Workup #AAFP
C-REACTIVE PROTEIN Discovered by Tillett & Francis in 1930. First identified as a substance in the serum
synthesized by the liver ... or minor elevation ... mg/L: Moderate elevation ... 10.0 mg/L: Marked elevation ... 50.0 mg/L: Severe elevation
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... tests algorithm ... initial response to abnormal ... magnitude of enzyme elevation ... #Algorithm #Hepatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
levels - Usually normal ... or slightly elevated ... Mild-to-moderate elevation ... or may not be elevated ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Elevated Lactate ... RBCs, muscle, liver ... upon damage • Normal ... It can remain elevated ... Idiosyncratic LDH Elevation
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