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diagnosis hepatology differential lfts hepatitis transaminitis abnormal alkaline alp phosphatase autoimmune causes chemistry comparison disease enzymes hellp hyophosphatasia icp injury
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... specific for the liver ... #FunctionTest # ... LFTs #Elevation
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Differential Diagnosis Algorithm ... Viral, Ischemia, AIH ... kwburak #LFTs #Elevated ... Transaminitis #Algorithm
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... Diagnosis Algorithm ... Other causes of elevation ... elevation DDX of ... #Elevation #Differential
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Mild jaundice, Elevated ... to 10-20-fold elevation ... Syndrome (Hemolysis, Elevated ... to 10-20-fold elevation ... of Pregnancy (AFLP
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Liver Chemistries ... specificity to elevated ... Bilirubin - +/- elevation ... or amyloid: • Elevation ... Enzyme Elevation
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... specificity to elevated ... Bilirubin - +/- elevation ... Enzyme Elevation ... differential #diagnosis #algorithm
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Differential Diagnosis Algorithm ... • Pregnancy - AFLP ... • Drugs • AIH ... Differential #Diagnosis #Algorithm
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
in 1923 Low ALP ... synthesized in: liver ... intracranial pressure - Elevated ... eliminated • Elevation ... phosphate &/or • Elevation
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
disease to acute liver ... hepatocellular pattern of liver ... IgG typically elevated ... If suspected, AIH ... (rare) - IgG Elevation
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... tests algorithm ... magnitude of enzyme elevation ... ALP, alkaline phosphatase ... LFTs #Abnormal #Algorithm
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