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diagnosis hematology differential management pulmonary thrombocytopenia activation algorithm blanching bruise cell disorders ecchymosis elevation hematomas hemostasis hepatology histiocytosis interpretation langerhans
Pulmonary Function Tests (PFTs) - Interpretation Algorithm • Normal • Pulmonary Hypertension, Anemia, Carboxyhemoglobinemia • Chest
Pulmonary Function ... Tests (PFTs) - ... #Pulmonary #FunctionTests ... #PFTs #Interpretation
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... SinaiBmoreIMRes #Liver #FunctionTest ... #LFTs #Elevation
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- History of bleeding ... K), H. pylori test ... country), thyroid function ... test, ANA (e.g. ... gastric bypass), LFT
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Bleeding and Bruising ... cascade is intact - test ... discern these causes ... are liver function ... tests (if not already
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
mass • Rapidly rising ... -> AML: Blast crises ... : Petechiae, bruising ... thrombocytopenia, or functional ... count • ↓Hg & PLT
Bleeding manifestations Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
Bleeding manifestations ... ecchymosis) is caused ... Excessive bruising ... Repeat tests at ... to be normal, PT
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
manifestations: from easy bruising ... purpura to mucosal bleeding ... thrombocytopenia • Liver function ... tests ↑ AST ↑ ALT ... ↑ PTT • ↑ Fibrin
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
anti-GBM) Other tests ... pericardial effusion) • PFTs ... Goodpasture's cause ... pulmonary capillaritis leading ... hematuria, RBC casts
Langerhans Cell Histiocytosis (LCH) Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
various tissues, leading ... PET-CT / MRI: Staging ... • Laboratory Tests ... : Blood tests to ... assess organ function
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