13 results
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG)
SAAG ≥ 1.1:
 - Ascitic protein
albumin gradient (SAAG ... ) SAAG ≥ 1.1: ... syndrome, Massive liver ... gradient #hepatology #differential ... #diagnosis #algorithm
Deciphering the SAAG - Serum to Ascites Albumin Gradient
Ascites is either made in the liver sinusoid
Deciphering the SAAG ... either made in the liver ... or not by the liver ... fibrosis) High SAAG ... Interpretation #Differential
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
hypertension (SAAG ... Liver disease ... - Acute fatty liver ... - Myxedema (SAAG ... Causes #diagnosis #differential
Ascites - Differential Diagnosis and Workup Algorithm

•
Perform paracentesis:
 • Cell count and diff 
 • Total
Ascites - Differential ... Diagnosis and Workup Algorithm ... • Calculate SAAG ... #Differential # ... Diagnosis #Algorithm
Peritonitis - Spontaneous vs Secondary vs Peritoneal Dialysis Associated Peritonitis
Spontaneous Bacterial Peritonitis
 • Cirrhosis (high SAAG)
Cirrhosis (high SAAG ... ) + ascites w/ PMN ... Features (abd pain ... Peritoneal #diagnosis #differential ... #ascites
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
Gradient (SAAG) ... - Differential ... - Massive liver ... - Acute fatty liver ... ischemia/infarction #SAAG
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... of portal HTN: ascites ... (SAAG>I.I), esophageal ... portal HTN: • Ascites ... sarcoidosis) • Liver
Causes of Ascites - Differential Diagnosis Algorithm
Portal Hypertension - Prehepatic:
 • Portal vein thrombosis
 • Splenic
- Differential ... Diagnosis Algorithm ... disease • Acute liver ... #Differential # ... Diagnosis #Algorithm
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... hepatocytes → Liver ... vomiting, abdominal pain ... develops (DIC, ascites ... infiltration) Differential
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... Diagnosis Algorithm ... disturbance (obstructed liver ... Highest • Bone • Liver ... Bone symptoms - Pain