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diagnosis hepatology differential lfts transaminitis biliary cirrhosis elevated elevation hepatitis interpretation laboratory pbc primary alkaline amyloid amyloidosis causes chemistry cholangitis
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
ALP - Biliary ... Transaminase, ALP ... / ULN ALT) / (ALP ... / ULN ALP) ... #FunctionTest #
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Differential Diagnosis Algorithm ... or AST > ALP): ... Wilsons, Pregnancy - AFLP ... Cholestatic Pattern (ALP
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Cholestasis • ALP ... augment synthesis of ALP ... disease • If ALP ... replaced by non-hepatic ... hemolysis) • ALP
Pulmonary Function Tests (PFTs) - Interpretation Algorithm • Normal • Pulmonary Hypertension, Anemia, Carboxyhemoglobinemia • Chest
Interpretation Algorithm ... • Normal • ... #Pulmonary #FunctionTests ... Interpretation #Algorithm
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Injury: • Hepatic ... specificity to elevated ALP ... GGT/5-NT: ↑ - ALP ... , ALP is from extrahepatic ... hemolysis) • ALP
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Alkaline Phosphatase (ALP ... ALP: - Enzymes ... - Increased ALP ... elevation DDX of Hepatic ... #Phosphatase #ALP
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
imaging: Normal ... • Histology: Normal-mild ... imaging: Hepatic ... of Pregnancy (AFLP ... diagnosis #icp #HELLP #AFLP
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Differential Diagnosis Algorithm ... • Pregnancy - AFLP ... disease US — Normal ... Differential #Diagnosis #Algorithm
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... tests algorithm ... initial response to abnormal ... ALP, alkaline phosphatase ... #Algorithm #Hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
cholestasis → Cirrhosis/Liver ... & AST normal or ... obstruction • ALP ... or higher • Liver ... malignancies, Hepatic
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