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diagnosis hepatology differential injury elevation lfts acute alkaline alp ascites cholangitis cirrhosis dili druginduced hepatitis hepatomegaly liverenzymes pbc phosphatase primary
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... specific for the liver ... ALP - Biliary ... SinaiBmoreIMRes #Liver ... #FunctionTest #
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... hepatitis, Acute biliary ... Extrahepatic • Biliary ... Differential #Diagnosis #Causes ... #Acute #algorithm
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Differential Diagnosis Algorithm ... disturbance (obstructed liver ... Highest • Bone • Liver ... Intestine - Other causes ... PSC - Other biliary
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... for alternative causes ... Benign/malignant biliary ... obstruction, Primary biliary ... Injury #Diagnosis #Algorithm
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Differential Diagnosis Algorithm ... Non-Malignant • Fatty Liver ... Cholangitis • Primary Biliary ... Differential #Diagnosis #Algorithm ... #Causes #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... Vascular Causes ... Extrahepatic - Biliary ... - Obstruction: Biliary ... differential #diagnosis #algorithm
Causes of Ascites - Differential Diagnosis Algorithm Portal Hypertension - Prehepatic: • Portal vein thrombosis • Splenic
Causes of Ascites ... Differential Diagnosis Algorithm ... disease • Acute liver ... failure • Primary biliary ... #Hepatology #causes
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Differential Diagnosis Algorithm ... Duct Stone • Biliary ... Differential #Diagnosis #Algorithm ... #Causes
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... 65 years PBC Pathophysiology ... intralobular bile ducts causes ... cholestasis → Cirrhosis/Liver ... or higher • Liver
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