15 results
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... specific for the liver ... #FunctionTest # ... LFTs #Elevation
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Liver Chemistry ... ALT: • AST: liver ... In liver, 80% of ... hepatocyte - Elevation ... Bilirubin #Hepatology #Pathophysiology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
no significant elevation ... disease and ILD • Liver ... Liver biopsies show ... + and CD8+ T cell ... +/CD8+ ratio are
Malaria - Plasmodium Life Cycle
1) Mosquito takes a blood meal (injects sporozoites)
Human Liver Stages
2) Infected liver
sporozoites) Human Liver ... Stages 2) Infected liver ... lifecycle #diagnosis #pathophysiology ... infectiousdiseases #cdc
Echinococcus Life Cycle
1) Adult in small intestine eggs
2) Embryonated egg in feces
3) Oncosphere hatches; penetrates intestinal
organs (commonly liver ... LifeCycle #diagnosis #pathophysiology ... infectiousdiseases #cdc
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
cardiomyopathy - Elevation ... regeneration, diffuse CD8 ... PM #Diagnosis #Pathophysiology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Muscles, Kidneys, Liver ... Rhabdomyolysis - AKI - Liver ... Collapse: • Pathophysiology ... tissue damage (AKI, Liver ... acidosis - CPK elevation
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
Hepatomegaly - Liver ... enzyme elevation ... during transient CD4 ... subset counts ↓ • Liver ... progression by slowing CD4
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver ... collection with EDTA Pathophysiology ... eliminated • Elevation ... phosphate &/or • Elevation
Schistosoma Life Cycle - Schistosomiasis
1) Eggs shed from infected human: in feces, in urine
2) Eggs hatch
portal blood in liver ... circulate to the liver ... Schistosomiasis #diagnosis #pathophysiology ... infectiousdiseases #cdc