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diagnosis algorithm hepatology lfts interpretation liver adrenal arteritis chemistry ck clinical creactiveprotein crp cystic differential echinococcosis echinococcus elevation endocrinology erythematosus
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
ALP ≥ 2x ULN R Value ... SinaiBmoreIMRes #Liver #FunctionTest ... LFTs #Elevation #Transaminitis
Pulmonary Function Tests (PFTs) - Interpretation Algorithm • Normal • Pulmonary Hypertension, Anemia, Carboxyhemoglobinemia • Chest
Algorithm • Normal ... #Pulmonary #FunctionTests
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Algorithm for Transaminitis ... AST): • US - Normal ... kwburak #LFTs #Elevated ... #Abnormal #Transaminitis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
specificity to elevated ... - If both are normal ... of ALP • Near normal ... differential #Hepatology #transaminitis ... #LFTs #RValue #
RHABDOMYOLYSIS • Characterized by skeletal muscle breakdown & necrosis. • Elevated Creatine kinase (CK) hallmark of rhabdomyolysis. • Defined based
• Elevated Creatine ... Defined based on CK values ... upper limit of normal ... CK is 1.5 days; elevated
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
activity - A low value ... If the value is ... levels - Usually normal ... or slightly elevated ... or may not be elevated
Adrenal Insufficiency Diagnosis Algorithm Test 1: Baseline AM Cortisol - Beware of major normal value -
Beware of major normal ... value - variation ... hydrocortisone - Falsely elevated
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
or sed rate): Value ... 50 in GCA, but normal ... values increase ... thrombocytosis, transaminitis
C-REACTIVE PROTEIN Discovered by Tillett & Francis in 1930. First identified as a substance in the serum
Lab values vary, ... than 0.3 mg/L: Normal ... 0.3 to 1.0 mg/L: Normal ... illness can falsely elevate
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
sedimentation rate + Normal ... sediment, and elevated ... Cytopenias • Cardiac valve ... flares • CRP normal
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