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diagnosis differential pharmacology nephrology algorithm management hyperkalemia causes pathophysiology table medications potassium diuretics cardiology endocrinology treatment raas renin adrenal hypokalemia
Diuretics - summary table Thiazides and Related Diuretics: HCTZ, Chlorthalidone, Metolazone, Indapamide, Bendroflumethiazide Loop Diuretics: Furosemide, Ethacrynic
Loop Diuretics: Furosemide ... Bumetanide, Torsemide Aldosterone ... table #thiazide #aldosterone
Overview of effects of diuretics and hormones involved in fluid homeostasis. #diruetic #diuretics #aldosterone #ADH #ANP #BNP #thiazide
#diuretics #aldosterone ... hydrocholorothyazide #loop #furosemide
Nephron Pathophysiology - Diuretic Sites of Action Diuretics 1) Acetazolamide/canagliflozin 2) Osmotic agents (mannitol, urearetics) 3) Loop agents (eg, furosemide) 4)
Loop agents (eg, furosemide ... Thiazides 5) Aldosterone
Thiazide diuretics Carbonic anhydrase inhibitors (e.g., acetazolamide) Nat-Cl symport Na and HCO;- reabsorption Aldosterone antagonists (e.g., spironolactone) Nat channel (indirect effect) Loop diuretics (e.g., furosemide) Amiloride, #triamterene Nat-K+-2CF symport Na channel (direct effect) #NaCI reabsorption
reabsorption Aldosterone ... diuretics (e.g., furosemide
K* uptake Acidosis [K*] in plasma t and cells Nat uptake ECF volume Spirono-lactone Diuretics Furosemide, thiazides Nat reabsorption in loop of Henle and
Spirono-lactone Diuretics Furosemide ... #Aldosterone 1
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Ethacrynic acid, Furosemide ... Receptor Antagonists (Aldosterone
Etiologies of Hypoaldosteronism Hyporeninemic Hypoaldosteronism (Low Renin, Low Aldosterone) - Diabetic Nephropathy - NSAIDs Non-Hyporeninemic Hypoaldosteronism (Normal
Low Renin, Low Aldosterone ... High Renin, Low Aldosterone ... Genetic disorders Aldosterone ... Normal or High Aldosterone ... ) - Aldosterone
Loop diuretic PO --> IV conversions Furosemide 40 mg PO = Furosemide 20 mg IV =
conversions Furosemide ... 40 mg PO = Furosemide ... Conversion #Table #Furosemide
Renin-Angiotensin-Aldosterone System (RAAS) #Pathophysiology #RAAS #Renin #Angiotensin #Aldosterone #System
Renin-Angiotensin-Aldosterone ... #Angiotensin #Aldosterone
Hyperaldosteronism - Etiologies of Mineralocorticoid Excess Primary Hyperaldosteronism (Normal or Low Renin, High Aldosterone) - Aldosterone-secreting
Low Renin, High Aldosterone ... ) - Aldosterone-secreting ... High Renin, High Aldosterone ... Normal or Low Aldosterone ... Diagnosis #Renin #Aldosterone
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