26 results
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... /Symptoms: • GH ... abn lipid • GH ... GrowthHormone #GH ... #FeedbackLoop #
Differential diagnoses for the neuro-ophthalmologic finding of diplopia.
Neoplastic: 
 • Intraorbital meningioma 
 • Pituitary adenoma
neuro-ophthalmologic finding of diplopia ... Pituitary adenoma (GH ... VI palsy) #Diplopia ... Differential #Diagnosis #Causes
Algorithm for the Evaluation of Diplopia: Diplopia has been explored previously on ddxof. The earlier algorithm
Evaluation of Diplopia ... : Diplopia has been ... This algorithm uses ... potential etiologic causes ... of diplopia.
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
time of onset of GH ... GH excess prior ... GH excess after ... • Other rare causes ... GrowthHormone #GH
Diplopia - Differential Diagnosis
Step 1: Consider Stroke
Step 2: Diplopia PLUS
 - Cavernous Sinus Syndrome
 - Infection
Diplopia - Differential ... Stroke Step 2: Diplopia ... Step 3: Isolated Diplopia ... to consider #Diplopia ... Diagnosis #Algorithm #Causes
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
GH stimulates ... adenomas are mixed GH ... level (↑Sens) - GH ... (Lanreotide) ± GH ... or refractory cases
Diplopia - Double Vision - Differential Diagnosis Algorithm
Clinical Pearls:
 • Diplopia is almost always binocular.
 •
Diplopia - Double ... Clinical Pearls: • Diplopia ... a mass as the cause ... Hyperthyroidism #Diplopia ... Diagnosis #Algorithm #Causes
Important Causes of Diplopia 
TIER 1-CRITICAL
Basilar artery thrombosis, Botulism, Basilar meningitis, Aneurysmn
TIER 2-EMERGENT:
Vertebral dissection, Myasthenia gravis,
Important Causes ... of Diplopia TIER ... Orbital apex mass #Diplopia
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
For pituitary masses ... following order; GH ... Headaches • Nausea ... Hydrocephalus • Diplopia
Acromegaly 
Caused by over-secretion of growth hormone (GH) from the pituitary gland. 
The condition is rare
Acromegaly Caused ... growth hormone (GH